C72 POSTERIOR WALL CHARACTERIZATION IN PATIENTS AFFECTED BY ATRIAL FIBRILLATION

Abstract Background Several clinical data in humans demonstrate that atrial fibrillation (AF) dominant frequencies and rotors are mostly localized on the posterior wall (PW), but correlation among these phenomena abnormal conduction properties during sinus (SR) paced rhythm (PR) has never been analyzed. Aims. To provide a characterization of left PW patients affected by persistent AF. In particular, purpose is to describe electrophysiological terms rotational focal activities AF, propagation uniformity SR functional sites definition PR. Methods Six from two EP centers have selected for this analysis. The procedures performed with CARTO3 mapping system. All EGMs collected Pentaray Octaray catheters. For each patient, module CARTOFINDER used AF identify areas shorter longer cycle length (site jump), activities; at least 15 PW. PR map were after electrical cardioversion exploit phenomena. created setting an extra beat coronary every three beats (pacing interval=local effective refractory period +40ms). Rotational identified associated signals characterized voltage amplitude (mV), signal duration (ms) fractionation. Results Abnormal recorded 33; one site jump was found most cases (77%, 10 out 13) it which 7 (70%) activity 2 (in PW). During rhythm, interest, we lower voltages (SR 1.9 ± 1,3mV, 1,7 1,15mV), fragmentation 52,7 8,85ms, 51,3 11,04ms) compared healthy tissue. Conclusion There strong between interest abnormalities This research work may pave way study represent relevant element maintenance, providing further step towards substrate